Women's Mental Health

Can PMDD Cause Suicidal Thoughts?

Paridhi Ajmera

27 अप्रैल 2025

6 minutes

Premenstrual Dysphoric Disorder (PMDD) is a severe, chronic medical condition that affects around 3–8% of menstruating individuals worldwide (Halbreich et al., 2003). While many people are familiar with the emotional ups and downs associated with premenstrual syndrome (PMS), PMDD is far more intense and debilitating. One of the most alarming symptoms reported by individuals with PMDD is the presence of suicidal thoughts. Understanding this link is crucial to offering proper help and breaking the stigma that often surrounds menstrual mental health.

What Is PMDD?

PMDD is a hormone-based mood disorder that arises during the luteal phase of the menstrual cycle, typically after ovulation and before menstruation begins. Unlike PMS, which involves mild to moderate symptoms, PMDD causes extreme mood shifts, depression, irritability, and anxiety. These symptoms usually resolve within a few days after menstruation starts but can disrupt personal relationships, work, and daily functioning during their peak (American Psychiatric Association, 2013).

The Link Between PMDD and Suicidal Thoughts

Research has consistently found that individuals with PMDD are at a significantly higher risk for suicidal ideation compared to those without PMDD. A study by Osborn et al. (2020) revealed that nearly 30% of participants with PMDD had actively considered suicide at some point during their symptomatic days. Fluctuations in hormones like estrogen and progesterone can deeply impact neurotransmitters such as serotonin, which regulate mood and emotional stability (Epperson et al., 2012). When these chemicals become imbalanced, it can lead to a sharp increase in depressive symptoms, hopelessness, and suicidal thinking.

How It Feels for Those Experiencing It

For individuals dealing with PMDD, suicidal thoughts are often described as intrusive and overwhelming, but they tend to lessen or disappear once menstruation begins. This cycle of despair can be terrifying, especially when the individual is aware that these thoughts are linked to their body’s hormonal rhythms but still feel powerless to control them. Many report a dual reality: knowing they do not want to die, yet feeling trapped by a temporary mental state that convinces them otherwise (Yonkers & Pearlstein, 1997).

Why Early Diagnosis and Support Matter

One of the biggest challenges with PMDD is that it is frequently misdiagnosed as bipolar disorder, major depression, or generalized anxiety disorder. Without the right diagnosis, individuals may not receive treatments specifically targeted at the hormonal root of their symptoms. Treatment approaches like SSRIs (Selective Serotonin Reuptake Inhibitors), hormonal therapies, lifestyle adjustments, and cognitive-behavioral therapy (CBT) have shown promise in alleviating both mood symptoms and suicidal thoughts (Pearlstein et al., 2005).

It is essential to listen without judgment when someone opens up about these experiences. Offering emotional support, helping them track their symptoms, and encouraging them to consult a healthcare professional can make a significant difference.

Closing Thoughts

Yes, PMDD can cause suicidal thoughts but it is important to remember that these thoughts are symptoms of a treatable disorder, not a reflection of the person’s true desires or character. Raising awareness about PMDD, advocating for better healthcare responses, and providing supportive environments can potentially save lives. If you or someone you know is struggling with suicidal thoughts linked to PMDD, reaching out to a mental health professional is not just important, it is life-affirming.

Disclaimer:
This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. If you or someone you know is experiencing suicidal thoughts, please seek help from a qualified healthcare provider immediately.

References

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.

Epperson, C. N., Steiner, M., & Hartlage, S. A. (2012). Premenstrual dysphoric disorder: Evidence for a new category for DSM-5. American Journal of Psychiatry, 169(5), 465–475. https://doi.org/10.1176/appi.ajp.2012.11081302

Halbreich, U., Borenstein, J., Pearlstein, T., & Kahn, L. S. (2003). The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD). Psychoneuroendocrinology, 28(3), 1–23. https://doi.org/10.1016/S0306-4530(03)00098-2

Osborn, E., Brooks, J., O’Brien, P. M., Wittchen, H. U., & Yonkers, K. A. (2020). Suicidal ideation in women with premenstrual dysphoric disorder: A systematic literature review. Archives of Women's Mental Health, 23(5), 585–592. https://doi.org/10.1007/s00737-020-01043-1

Pearlstein, T., Halbreich, U., Batzar, E., Brown, C. S., Endicott, J., & Yonkers, K. (2005). Psychotropic treatment of premenstrual dysphoric disorder: Results from a double-blind, placebo-controlled, crossover study. Journal of Clinical Psychiatry, 66(5), 604–610. https://doi.org/10.4088/JCP.v66n0506

Yonkers, K. A., & Pearlstein, T. (1997). Premenstrual dysphoric disorder: Etiology and treatment. Annual Review of Medicine, 48, 447–456. https://doi.org/10.1146/annurev.med.48.1.447

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Location

New Delhi, India

Send a message

Use our contact form to get in touch with us if you would like to work or partner with us, or have questions!

HealCycle © 2025. Adapted from design by Goran Babarogic

CIN: U62090DL2024PTC437330

HealCycle

Location

New Delhi, India

Send a message

Use our contact form to get in touch with us if you would like to work or partner with us, or have questions!

HealCycle © 2025. Adapted from design by Goran Babarogic

CIN: U62090DL2024PTC437330